:root{--bg:#e7eef4;--bg-deep:#d2dde8;--ink:#0a1c2e;--ink-soft:#36506a;--muted:#5a7186;--paper:#f8fbfd;--paper-elevated:#ffffff;--accent:#0f766e;--accent-bright:#14b8a6;--accent-soft:rgba(15,118,110,0.10);--accent-ink:#042f2e;--warn:#b45309;--danger:#b91c1c;--ok:#047857;--line:rgba(10,28,46,0.11);--line-strong:rgba(10,28,46,0.18);--shadow:0 18px 50px rgba(10,28,46,0.08);--shadow-sm:0 8px 22px rgba(10,28,46,0.06);--font-display:"Fraunces","Noto Serif SC","Songti SC",Georgia,serif;--font-body:"Outfit","PingFang SC","Hiragino Sans GB","Microsoft YaHei","HarmonyOS Sans SC","MiSans","Noto Sans SC","Noto Sans CJK SC",sans-serif;--font-mono:"JetBrains Mono",ui-monospace,monospace;--radius:0.55rem;--radius-lg:1rem;--h1-size:clamp(2rem,4.2vw,2.65rem);--h1-lh:1.15;--h1-tracking:-0.02em;--h2-size:clamp(1.35rem,2.4vw,1.6rem);--h2-lh:1.25;--h3-size:clamp(1.05rem,1.6vw,1.2rem);--h3-lh:1.35}*{box-sizing:border-box}html{overflow-x:hidden;text-size-adjust:100%}body,html{margin:0;min-height:100%;min-height:100dvh;color:var(--ink);font-family:var(--font-body);background:radial-gradient(900px 520px at 88% -10%,rgba(20,184,166,.18),transparent 55%),radial-gradient(700px 480px at -10% 20%,rgba(11,31,51,.08),transparent 50%),linear-gradient(165deg,var(--bg) 0,var(--bg-deep) 100%)}body{position:relative;min-height:100vh}a{color:inherit}.grain{pointer-events:none;position:fixed;inset:0;z-index:0;opacity:.35;background-image:url("data:image/svg+xml,%3Csvg viewBox='0 0 200 200' xmlns='http://www.w3.org/2000/svg'%3E%3Cfilter id='n'%3E%3CfeTurbulence type='fractalNoise' baseFrequency='0.85' numOctaves='3' stitchTiles='stitch'/%3E%3C/filter%3E%3Crect width='100%25' height='100%25' filter='url(%23n)' opacity='0.45'/%3E%3C/svg%3E");mix-blend-mode:multiply}.hero,.page,.section,.site-footer,.site-header{position:relative;z-index:1}.site-header{display:flex;align-items:center;justify-content:space-between;gap:1rem;width:min(1120px,calc(100% - 2rem));margin:0 auto;padding:1.1rem 0}.logo{display:inline-flex;align-items:center;gap:.55rem;text-decoration:none;font-family:var(--font-display);font-weight:700;font-size:1.25rem;letter-spacing:.02em;flex:0 0 auto}.logo-text{white-space:nowrap}.logo-mark{width:.85rem;height:.85rem;border-radius:2px;background:linear-gradient(135deg,var(--accent-bright),var(--accent));box-shadow:0 0 0 3px rgba(15,118,110,.18);animation:pulse-mark 2.8s ease-in-out infinite}.nav{display:flex;align-items:center;flex-wrap:wrap;gap:.35rem .85rem}.nav-link{text-decoration:none;color:var(--ink-soft);font-weight:500;font-size:.95rem;padding:.35rem .2rem;transition:color .16s ease;word-break:keep-all}.nav-link:hover{color:var(--ink)}.nav-cta{text-decoration:none;font-weight:600;font-size:.9rem;padding:.45rem .85rem;border-radius:999px;background:var(--ink);color:var(--paper);transition:transform .16s ease,background .16s ease;word-break:keep-all;white-space:nowrap}.nav-cta:hover{transform:translateY(-1px);background:#12324d}.page{width:min(1120px,calc(100% - 2rem));margin:0 auto;padding:.5rem 0 4rem}.hero{display:grid;grid-template-columns:1.15fr .85fr;grid-gap:2rem;gap:2rem;align-items:stretch;min-height:min(72vh,640px);padding:1.5rem 0 2.5rem}.hero-copy{display:flex;flex-direction:column;justify-content:center;animation:rise .7s cubic-bezier(.2,.8,.2,1) both}.kicker{font-family:var(--font-mono);font-size:.78rem;letter-spacing:.14em;text-transform:uppercase;color:var(--accent)}.brand,.kicker{margin:0 0 .85rem}.brand{font-family:var(--font-display);font-size:clamp(3.2rem,9vw,5.6rem);font-weight:700;line-height:.95;letter-spacing:-.02em;color:var(--ink)}.lead{margin:0 0 1.75rem;max-width:34rem;font-size:1.12rem;line-height:1.7;color:var(--ink-soft)}.actions{display:flex;flex-wrap:wrap;gap:.75rem}.btn{display:inline-flex;align-items:center;justify-content:center;gap:.4rem;padding:.85rem 1.25rem;border-radius:var(--radius);text-decoration:none;font-weight:600;border:1px solid transparent;cursor:pointer;font:inherit;transition:transform .16s ease,background .16s ease,border-color .16s ease,box-shadow .16s ease}.btn:hover{transform:translateY(-2px)}.btn-primary{background:var(--accent);color:#ecfeff;box-shadow:0 10px 24px rgba(15,118,110,.28)}.btn-primary:hover{background:#0d9488}.btn-secondary{background:var(--paper);border-color:var(--line);color:var(--ink)}.btn-secondary:hover{border-color:rgba(15,118,110,.45)}.hero-visual{position:relative;border-radius:1rem;overflow:hidden;background:linear-gradient(160deg,#0b1f33,#12324d 45%,#0f766e 120%);box-shadow:var(--shadow);animation:rise .9s cubic-bezier(.2,.8,.2,1) .12s both;min-height:320px}.hero-visual:before{content:"";background-image:linear-gradient(rgba(255,255,255,.06) 1px,transparent 0),linear-gradient(90deg,rgba(255,255,255,.06) 1px,transparent 0);background-size:36px 36px;-webkit-mask-image:radial-gradient(circle at 40% 40%,black 20%,transparent 75%);mask-image:radial-gradient(circle at 40% 40%,black 20%,transparent 75%)}.constellation,.hero-visual:before{position:absolute;inset:0}.node{position:absolute;width:10px;height:10px;border-radius:50%;background:#5eead4;box-shadow:0 0 0 6px rgba(94,234,212,.15);animation:node-glow 2.4s ease-in-out infinite}.node:first-child{top:22%;left:28%}.node:nth-child(2){top:38%;left:58%;animation-delay:.3s}.node:nth-child(3){top:62%;left:36%;animation-delay:.55s}.node:nth-child(4){top:48%;left:78%;animation-delay:.8s}.node:nth-child(5){top:72%;left:68%;animation-delay:1s}.link-line{position:absolute;height:1px;background:linear-gradient(90deg,transparent,rgba(94,234,212,.65),transparent);transform-origin:left center;animation:draw-line 1.4s ease both}.visual-caption{position:absolute;left:1.25rem;right:1.25rem;bottom:1.25rem;color:rgba(247,250,252,.88);font-size:.92rem;line-height:1.5}.visual-caption strong{display:block;font-family:var(--font-display);font-size:1.15rem;margin-bottom:.25rem;color:#fff}.section{margin-top:1.5rem;padding:1.75rem;border-radius:var(--radius-lg);background:color-mix(in srgb,var(--paper) 82%,var(--paper-elevated));border:1px solid var(--line);box-shadow:var(--shadow);animation:rise .8s cubic-bezier(.2,.8,.2,1) .18s both}.section h2,h2.section-title{margin:0 0 .4rem;font-family:var(--font-display);font-size:var(--h2-size);font-weight:700;line-height:var(--h2-lh);letter-spacing:-.015em;color:var(--ink)}.section h3,h3.section-subtitle{margin:0 0 .35rem;font-family:var(--font-display);font-size:var(--h3-size);font-weight:650;line-height:var(--h3-lh);color:var(--ink)}.section-lead{margin:0 0 1.25rem;color:var(--muted);max-width:40rem;line-height:1.6}.pulse-list{list-style:none;margin:0;padding:0;display:grid;grid-gap:.65rem;gap:.65rem}.pulse-list li{display:grid;grid-template-columns:auto 1fr auto;grid-gap:.75rem;gap:.75rem;align-items:baseline;padding:.75rem .85rem;border-radius:.55rem;background:rgba(11,31,51,.03);border:1px solid transparent;transition:border-color .16s ease,background .16s ease}.pulse-list li:hover{border-color:rgba(15,118,110,.25);background:rgba(15,118,110,.05)}.pulse-list a{text-decoration:none;font-weight:600}.pulse-list a:hover{color:var(--accent)}.mono{font-family:var(--font-mono);font-size:.78rem;color:var(--muted)}.site-footer{width:min(1120px,calc(100% - 2rem));margin:0 auto 2rem;padding-top:1.25rem;border-top:1px solid var(--line);display:flex;flex-wrap:wrap;justify-content:space-between;gap:1rem}.footer-row{min-width:0}.footer-brand{margin:0;font-family:var(--font-display);font-weight:600}.footer-note{margin:.2rem 0 0;color:var(--muted);font-size:.9rem}.footer-links{display:flex;flex-wrap:wrap;gap:.85rem 1.1rem;align-items:center}.footer-links a{text-decoration:none;color:var(--ink-soft);font-size:.92rem}.footer-links a:hover{color:var(--accent)}.hub-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));grid-gap:1rem;gap:1rem}.hub-tile{display:block;text-decoration:none;padding:1.25rem 1.3rem;border-radius:.85rem;border:1px solid var(--line);background:var(--paper);transition:transform .16s ease,border-color .16s ease,box-shadow .16s ease}.hub-tile:hover{transform:translateY(-2px);border-color:rgba(15,118,110,.35);box-shadow:var(--shadow)}.hub-tile h3{margin:0 0 .4rem;font-family:var(--font-display);font-size:var(--h3-size);font-weight:650;line-height:var(--h3-lh);color:var(--ink)}.hub-tile p{margin:0;color:var(--muted);line-height:1.55;font-size:.95rem}.hub-tile .tag{display:inline-block;margin-bottom:.55rem;font-family:var(--font-mono);font-size:.72rem;letter-spacing:.08em;text-transform:uppercase;color:var(--accent)}.note-banner{margin:1rem 0 1.5rem;padding:.9rem 1rem;border-radius:.65rem;background:rgba(180,83,9,.1);border:1px solid rgba(180,83,9,.25);color:#7c2d12;line-height:1.55;font-size:.95rem}.stats{display:grid;grid-template-columns:repeat(4,minmax(0,1fr));grid-gap:.85rem;gap:.85rem;margin:1.25rem 0 1.75rem}.stat{padding:1rem 1.05rem;border-radius:.75rem;background:var(--paper);border:1px solid var(--line)}.stat .label{display:block;font-family:var(--font-mono);font-size:.72rem;letter-spacing:.06em;text-transform:uppercase;color:var(--muted);margin-bottom:.35rem}.stat .value{font-family:var(--font-display);font-size:1.85rem;font-weight:700;line-height:1}.panels{display:grid;grid-template-columns:1.2fr .8fr;grid-gap:1rem;gap:1rem}.panel{padding:1.15rem 1.2rem 1.25rem;border-radius:.85rem;background:var(--paper);border:1px solid var(--line)}.panel h3{margin:0 0 .85rem;font-family:var(--font-display);font-size:1.15rem}.health-list{list-style:none;margin:0;padding:0;display:grid;grid-gap:.55rem;gap:.55rem}.health-list li{display:flex;justify-content:space-between;gap:.75rem;align-items:center;padding:.65rem .7rem;border-radius:.5rem;background:rgba(11,31,51,.03)}.badge{font-family:var(--font-mono);font-size:.72rem;padding:.2rem .45rem;border-radius:999px;white-space:nowrap}.badge-ok{background:rgba(4,120,87,.12);color:var(--ok)}.badge-bad{background:rgba(185,28,28,.12);color:var(--danger)}.feed{list-style:none;margin:0;padding:0;display:grid;grid-gap:.55rem;gap:.55rem;max-height:420px;overflow:auto}.feed li{padding-bottom:.55rem;border-bottom:1px solid var(--line)}.feed li:last-child{border-bottom:0}.feed a{text-decoration:none;font-weight:600}.feed a:hover{color:var(--accent)}.page-title,h1.page-title{margin:.5rem 0 .4rem;font-family:var(--font-display);font-size:var(--h1-size);font-weight:700;line-height:var(--h1-lh);letter-spacing:var(--h1-tracking);color:var(--ink)}.page-lead{margin:0 0 .5rem;color:var(--muted);max-width:40rem;line-height:1.6}.flow{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));grid-gap:.85rem;gap:.85rem;margin:1.25rem 0 1.5rem}.flow-step{display:flex;gap:.75rem;align-items:flex-start;padding:1rem 1.05rem;border-radius:.85rem;background:var(--paper);border:1px solid var(--line)}.flow-num{flex:0 0 auto;width:1.75rem;height:1.75rem;border-radius:999px;display:grid;place-items:center;background:var(--ink);color:var(--paper);font-family:var(--font-mono);font-size:.85rem}.flow-step p{margin:.25rem 0 0;color:var(--muted);font-size:.9rem;line-height:1.45}.rules-banner{margin:0 0 1.5rem;padding:.95rem 1.05rem;border-radius:.75rem;background:rgba(185,28,28,.08);border:1px solid rgba(185,28,28,.22);color:#7f1d1d;line-height:1.6;font-size:.95rem}.help-form{display:grid;grid-gap:.85rem;gap:.85rem;max-width:40rem}.help-form label{display:grid;grid-gap:.35rem;gap:.35rem;font-weight:600;font-size:.92rem}.help-form input,.help-form select,.help-form textarea{font:inherit;font-weight:400;padding:.7rem .8rem;border-radius:.45rem;border:1px solid var(--line);background:#fff;color:var(--ink)}.form-note{margin:0;color:var(--muted);font-size:.9rem;line-height:1.55}.help-form button{justify-self:start;cursor:pointer;border:0}.check-list{margin:0;padding-left:1.15rem;color:var(--ink-soft);line-height:1.7}.check-list a{color:var(--accent)}.graph-wrap{display:grid;grid-template-columns:minmax(0,1.35fr) minmax(0,.85fr);grid-gap:1rem;gap:1rem;margin-top:1.25rem;min-width:0}.paper-svg{display:block;width:100%;height:auto;max-height:min(70vh,560px);border:1px solid var(--line)}.graph-detail,.paper-svg{background:var(--paper);border-radius:.85rem}.graph-detail{min-width:0;padding:1rem 1.1rem;border:1px solid var(--line)}.graph-detail h3{margin:.35rem 0;font-family:var(--font-display);font-size:1.15rem;overflow-wrap:anywhere}.graph-detail .tag{font-family:var(--font-mono);font-size:.72rem;letter-spacing:.06em;text-transform:uppercase;color:var(--accent)}.linkish{background:none;border:0;padding:0;font:inherit;font-weight:600;text-align:left;color:var(--ink);cursor:pointer;overflow-wrap:anywhere}.linkish:hover:not(:disabled){color:var(--accent)}.linkish:disabled{opacity:.55;cursor:not-allowed}.tool-filters{display:flex;flex-wrap:wrap;gap:.45rem;margin:0 0 1rem}.chip{font:inherit;font-size:.85rem;padding:.35rem .7rem;border-radius:999px;border:1px solid var(--line);background:var(--paper);color:var(--ink-soft);cursor:pointer;word-break:keep-all}.chip-on{background:var(--ink);color:var(--paper);border-color:var(--ink)}.hub-tile h3,.pulse-list li{min-width:0}@keyframes rise{0%{opacity:0;transform:translateY(14px)}to{opacity:1;transform:none}}@keyframes pulse-mark{0%,to{box-shadow:0 0 0 3px rgba(15,118,110,.18)}50%{box-shadow:0 0 0 7px rgba(15,118,110,.08)}}@keyframes node-glow{0%,to{transform:scale(1);opacity:.85}50%{transform:scale(1.25);opacity:1}}@keyframes draw-line{0%{opacity:0;transform:scaleX(0)}to{opacity:1;transform:scaleX(1)}}@media (max-width:1200px){.stats{grid-template-columns:repeat(4,minmax(0,1fr))}}@media (max-width:860px){.flow,.graph-wrap,.hero,.hub-grid,.panels,.stats{grid-template-columns:1fr}.stats{grid-template-columns:repeat(2,minmax(0,1fr))}.site-header{flex-direction:column;align-items:flex-start}}@media (max-width:480px){.hub-grid,.pulse-list li,.stats{grid-template-columns:1fr}.hero-visual{min-height:220px}.nav-link{font-size:.88rem}.logo-text,.nav-cta{white-space:nowrap}}.rnaseq-form,.rnaseq-studio{display:grid;grid-gap:1rem;gap:1rem}.rnaseq-panel{padding:1.1rem 1.15rem 1.2rem;border-radius:1rem;background:var(--paper);border:1px solid var(--line);box-shadow:var(--shadow)}.rnaseq-panel-head h2{margin:0 0 .25rem;font-family:var(--font-display);font-size:var(--h2-size);font-weight:700;line-height:var(--h2-lh);letter-spacing:-.015em;color:var(--ink)}.rnaseq-panel-head p{margin:0 0 .9rem;color:var(--muted);font-size:.92rem;line-height:1.5}.rnaseq-file{display:grid;grid-gap:.35rem;gap:.35rem;font-weight:600;font-size:.92rem;margin-bottom:.75rem}.rnaseq-file-secondary{opacity:.92}.rnaseq-file input[type=file]{font:inherit;font-weight:400}.rnaseq-sample-pool{margin:.35rem 0 1rem;padding:.85rem .9rem;border-radius:.75rem;background:rgba(11,31,51,.03);border:1px dashed var(--line)}.rnaseq-pool-title{font-size:.85rem;color:var(--muted);margin-bottom:.55rem}.rnaseq-card-samples,.rnaseq-chips{display:flex;flex-wrap:wrap;gap:.4rem}.rnaseq-chip{border:1px solid var(--line);background:#fff;color:var(--ink);border-radius:999px;padding:.28rem .7rem;font-size:.82rem;cursor:pointer;transition:transform .12s ease,border-color .12s ease,background .12s ease}.rnaseq-chip:hover:not(:disabled){transform:translateY(-1px);border-color:var(--accent)}.rnaseq-chip:disabled{opacity:.55;cursor:not-allowed}.rnaseq-chip.is-assigned{font-weight:600}.rnaseq-group-grid{display:grid;grid-template-columns:repeat(auto-fill,minmax(240px,1fr));grid-gap:.85rem;gap:.85rem;margin-bottom:.85rem}.rnaseq-group-card{--group-accent:var(--accent);display:grid;grid-gap:.65rem;gap:.65rem;padding:.9rem .95rem;border-radius:.9rem;border:1.5px solid color-mix(in srgb,var(--group-accent) 45%,var(--line));background:linear-gradient(180deg,color-mix(in srgb,var(--group-accent) 10%,#fff) 0,#fff 42%);cursor:pointer;transition:box-shadow .16s ease,transform .16s ease,border-color .16s ease}.rnaseq-group-card:hover{transform:translateY(-1px);box-shadow:0 10px 28px rgba(11,31,51,.08)}.rnaseq-group-card.is-active{border-color:var(--group-accent);box-shadow:0 0 0 3px color-mix(in srgb,var(--group-accent) 22%,transparent)}.rnaseq-group-card-head{display:flex;align-items:center;gap:.4rem}.rnaseq-group-name{flex:1 1;min-width:0;font:inherit;font-weight:700;font-size:1.02rem;border:0;border-bottom:1px dashed color-mix(in srgb,var(--group-accent) 35%,transparent);background:transparent;color:var(--ink);padding:.15rem .1rem}.rnaseq-icon-btn{border:0;background:rgba(11,31,51,.06);width:1.7rem;height:1.7rem;border-radius:999px;cursor:pointer;font-size:1.05rem;line-height:1;color:var(--ink-soft)}.rnaseq-inline-field{display:grid;grid-gap:.25rem;gap:.25rem;font-size:.82rem;font-weight:600;color:var(--muted)}.rnaseq-inline-field select,.rnaseq-options-grid input,.rnaseq-options-grid select{font:inherit;font-weight:500;color:var(--ink);border:1px solid var(--line);border-radius:.45rem;padding:.45rem .55rem;background:#fff}.rnaseq-color-row{display:grid;grid-gap:.35rem;gap:.35rem;font-size:.82rem;font-weight:600;color:var(--muted)}.rnaseq-swatches{display:flex;flex-wrap:wrap;align-items:center;gap:.35rem}.rnaseq-swatch{width:1.2rem;height:1.2rem;border-radius:999px;border:2px solid #fff;box-shadow:0 0 0 1px rgba(11,31,51,.18);cursor:pointer;padding:0}.rnaseq-swatch.is-on{box-shadow:0 0 0 2px var(--ink)}.rnaseq-swatches input[type=color]{width:1.6rem;height:1.4rem;padding:0;border:0;background:transparent;cursor:pointer}.rnaseq-card-foot{font-size:.75rem;color:var(--muted)}.rnaseq-contrast-preview{margin-top:.85rem;padding-top:.75rem;border-top:1px solid var(--line)}.rnaseq-contrast-preview h3,.rnaseq-venn-modes h3{margin:0 0 .45rem;font-size:.95rem}.rnaseq-contrast-preview ul{margin:0;padding-left:1.1rem;color:var(--ink-soft);line-height:1.55}.rnaseq-options-grid{display:grid;grid-template-columns:repeat(auto-fill,minmax(160px,1fr));grid-gap:.75rem;gap:.75rem;margin-bottom:.85rem}.rnaseq-options-grid label{display:grid;grid-gap:.3rem;gap:.3rem;font-size:.88rem;font-weight:600}.rnaseq-check-row{display:flex;flex-wrap:wrap;gap:.85rem 1.15rem;margin-bottom:.85rem;font-size:.92rem}.rnaseq-check-row label{display:inline-flex;align-items:center;gap:.35rem;font-weight:600}.rnaseq-venn-grid{display:grid;grid-template-columns:repeat(auto-fill,minmax(200px,1fr));grid-gap:.65rem;gap:.65rem}.rnaseq-venn-card{display:grid;grid-template-columns:auto 1fr;grid-template-rows:auto auto;grid-column-gap:.5rem;column-gap:.5rem;grid-row-gap:.15rem;row-gap:.15rem;padding:.75rem .8rem;border-radius:.75rem;border:1px solid var(--line);background:rgba(11,31,51,.02);cursor:pointer}.rnaseq-venn-card input{grid-row:1/span 2;margin-top:.2rem}.rnaseq-venn-card strong{font-size:.9rem}.rnaseq-venn-card span{font-size:.8rem;color:var(--muted);line-height:1.4}.rnaseq-venn-card.is-on{border-color:color-mix(in srgb,var(--accent) 55%,var(--line));background:color-mix(in srgb,var(--accent) 8%,#fff)}@media (max-width:720px){.rnaseq-group-grid{grid-template-columns:1fr}}.rnaseq-group-card.is-drop{border-color:var(--group-accent,var(--accent));box-shadow:0 0 0 3px color-mix(in srgb,var(--group-accent,var(--accent)) 35%,transparent);background:color-mix(in srgb,var(--group-accent,var(--accent)) 8%,#fff)}.rnaseq-contrast-actions{display:flex;gap:.5rem;margin:.5rem 0 .75rem}.rnaseq-contrast-grid{display:grid;grid-template-columns:repeat(auto-fill,minmax(220px,1fr));grid-gap:.5rem;gap:.5rem}.rnaseq-contrast-card{display:flex;gap:.55rem;align-items:flex-start;padding:.65rem .75rem;border-radius:10px;border:1px solid var(--line);background:rgba(11,31,51,.02);cursor:pointer}.rnaseq-contrast-card.is-on{border-color:color-mix(in srgb,var(--accent) 55%,var(--line));background:color-mix(in srgb,var(--accent) 8%,#fff)}.rnaseq-contrast-card input{margin-top:.15rem}.ncbi-wizard .ncbi-steps{display:flex;flex-wrap:wrap;gap:.5rem 1rem;list-style:none;padding:0;margin:0 0 1rem;color:var(--muted);font-size:.9rem}.ncbi-wizard .ncbi-steps li.is-on{color:var(--ink,#0b1f33);font-weight:600}.tools-history{margin-top:1.75rem;padding-top:1rem;border-top:1px solid color-mix(in srgb,var(--muted,#667) 35%,transparent)}.tools-history-head{display:flex;align-items:center;justify-content:space-between;gap:.75rem;margin-bottom:.5rem}.tools-history-head h2{margin:0;font-family:var(--font-display);font-size:var(--h2-size);font-weight:700;line-height:var(--h2-lh);color:var(--ink)}.tools-quota{font-size:.9rem;color:var(--muted,#556);margin:.25rem 0 .75rem}.tools-quota.is-warn{color:#9a3412;font-weight:600}.tools-history-table-wrap{overflow-x:auto}.tools-history-table{width:100%;border-collapse:collapse;font-size:.9rem}.tools-history-table td,.tools-history-table th{text-align:left;padding:.45rem .55rem;border-bottom:1px solid color-mix(in srgb,var(--muted,#667) 28%,transparent);vertical-align:top}.tools-status{display:inline-block;padding:.1rem .45rem;border-radius:999px;background:#e2e8f0;font-size:.8rem}.tools-status-dry_run,.tools-status-succeeded{background:#d1fae5;color:#065f46}.tools-status-failed{background:#fee2e2;color:#991b1b}.tools-status-queued,.tools-status-running{background:#e0e7ff;color:#3730a3}.rnaseq-ann-box{margin:1rem 0;padding:.85rem 1rem;border:1px dashed color-mix(in srgb,var(--muted,#667) 45%,transparent);border-radius:12px;background:color-mix(in srgb,#0f766e 6%,white)}.rnaseq-ann-box h3{margin:0 0 .4rem;font-size:1rem}.rnaseq-ann-list{margin:.5rem 0 0;padding-left:1.1rem;font-size:.85rem}.ncbi-mode-cards{display:grid;grid-template-columns:repeat(auto-fit,minmax(220px,1fr));grid-gap:.75rem;gap:.75rem;margin:.75rem 0 1rem}.ncbi-mode-card{border:1px solid color-mix(in srgb,var(--muted,#667) 35%,transparent);border-radius:12px;padding:.75rem .9rem;background:#fff}.ncbi-mode-card.is-on{border-color:#0f766e;box-shadow:0 0 0 2px color-mix(in srgb,#0f766e 25%,transparent)}.ncbi-mode-card h3{margin:0 0 .35rem;font-size:1rem}.ncbi-mode-card p{margin:0;font-size:.9rem;color:var(--muted,#445)}.ncbi-checklist{margin:.5rem 0 1rem;padding:.75rem .9rem;border-radius:12px;background:#f8fafc;border:1px solid color-mix(in srgb,var(--muted,#667) 25%,transparent)}.ncbi-checklist-head{display:flex;flex-wrap:wrap;justify-content:space-between;gap:.5rem;align-items:baseline}.ncbi-checklist-head h3{margin:0}.ncbi-checklist-list{list-style:none;padding:0;margin:.5rem 0}.ncbi-checklist-list li{margin:.35rem 0}.ncbi-checklist-list li.is-done label strong{color:#065f46}.ncbi-checklist-list label{display:flex;gap:.55rem;align-items:flex-start}.ncbi-checklist-list label span{display:flex;flex-direction:column;gap:.1rem}.ncbi-checklist-list label em{font-style:normal;font-size:.8rem;color:var(--muted,#667)}.tool-post-list{list-style:none;padding:0;margin:1rem 0 0;display:grid;grid-gap:.85rem;gap:.85rem}.tool-post-card{border:1px solid color-mix(in oklab,var(--border,#d0d7de) 100%,transparent);border-radius:12px;padding:1rem 1.1rem;background:color-mix(in oklab,var(--card,#fff) 92%,transparent)}.tool-post-card h3{margin:.35rem 0 .4rem;font-size:1.05rem}.tool-post-card p{margin:.25rem 0;line-height:1.55}.tool-post-meta{display:flex;flex-wrap:wrap;gap:.4rem .65rem;align-items:center}.tool-post-tags{display:flex;flex-wrap:wrap;gap:.35rem;margin-top:.5rem}.tool-resolve-modal{position:fixed;inset:0;z-index:80;display:grid;place-items:center;padding:1rem;background:rgba(10,16,28,.45)}.tool-resolve-modal .help-form{width:min(560px,100%);max-height:min(90vh,900px);overflow:auto;background:var(--bg,#fff);border-radius:14px;padding:1.1rem 1.2rem 1.25rem;box-shadow:0 18px 50px rgba(0,0,0,.22)}.page-kicker{margin:0 0 .35rem;font-size:.75rem;letter-spacing:.12em;text-transform:uppercase;color:var(--accent)}.page-crumb,.page-kicker{font-family:var(--font-mono)}.page-crumb{margin:0 0 .65rem;font-size:.85rem;color:var(--muted)}.page-crumb a{color:var(--accent);text-decoration:none}.page-crumb a:hover{text-decoration:underline}.module-hero{display:grid;grid-gap:.35rem;gap:.35rem;margin:0 0 1.25rem;padding:1.15rem 1.25rem 1.2rem;border-radius:var(--radius-lg);border:1px solid var(--line);background:linear-gradient(135deg,rgba(20,184,166,.1),transparent 55%),color-mix(in srgb,var(--paper) 70%,white);box-shadow:var(--shadow-sm)}.module-hero .page-title{margin:.15rem 0 .25rem}.module-hero .page-lead{margin:0}.ai-studio{display:grid;grid-gap:1rem;gap:1rem}.ai-layout{display:grid;grid-template-columns:minmax(0,1.55fr) minmax(240px,.7fr);grid-gap:1rem;gap:1rem;align-items:start}.ai-chat-panel,.ai-side-panel{padding:1.1rem 1.15rem 1.2rem;border-radius:var(--radius-lg);background:var(--paper);border:1px solid var(--line);box-shadow:var(--shadow-sm)}.ai-chat-panel h2,.ai-side-panel h2{margin:0 0 .35rem;font-family:var(--font-display);font-size:var(--h2-size);font-weight:700;line-height:var(--h2-lh);color:var(--ink)}.ai-meta{display:flex;flex-wrap:wrap;gap:.45rem .75rem;margin:0 0 .9rem;color:var(--muted);font-size:.88rem}.ai-pill{display:inline-flex;align-items:center;gap:.3rem;padding:.2rem .55rem;border-radius:999px;background:var(--accent-soft);color:var(--accent-ink);border:1px solid rgba(15,118,110,.18);font-size:.8rem;font-weight:600}.ai-pill.is-warn{background:rgba(180,83,9,.12);color:#7c2d12;border-color:rgba(180,83,9,.28)}.ai-pill.is-ok{background:rgba(4,120,87,.12);color:#065f46;border-color:rgba(4,120,87,.25)}.ai-thread{display:grid;grid-gap:.75rem;gap:.75rem;min-height:280px;max-height:min(52vh,520px);overflow:auto;padding:.85rem;border-radius:.85rem;background:rgba(10,28,46,.03);border:1px solid var(--line);margin-bottom:.9rem}.ai-msg{max-width:92%;padding:.75rem .9rem;border-radius:.85rem;line-height:1.6;white-space:pre-wrap;word-break:break-word;font-size:.95rem}.ai-msg-user{justify-self:end;background:linear-gradient(160deg,#0f766e,#0d9488);color:#ecfeff;border-bottom-right-radius:.3rem}.ai-msg-assistant{justify-self:start;background:var(--paper-elevated);border:1px solid var(--line);color:var(--ink);border-bottom-left-radius:.3rem;box-shadow:var(--shadow-sm)}.ai-msg-system{justify-self:center;max-width:100%;background:transparent;color:var(--muted);font-size:.88rem;text-align:center;padding:.35rem .5rem}.ai-composer{display:grid;grid-gap:.65rem;gap:.65rem}.ai-composer-row{display:grid;grid-template-columns:minmax(0,1fr) auto;grid-gap:.55rem;gap:.55rem;align-items:end}.ai-composer textarea{width:100%;min-height:96px;resize:vertical;font:inherit;padding:.75rem .85rem;border-radius:.75rem;border:1px solid var(--line-strong);background:#fff;color:var(--ink);line-height:1.5}.ai-composer textarea:focus{outline:2px solid rgba(20,184,166,.35);border-color:var(--accent)}.ai-scene-row{display:flex;flex-wrap:wrap;gap:.4rem}.ai-scene-row .chip-on{background:var(--accent);border-color:var(--accent);color:#ecfeff}.ai-side-list{list-style:none;margin:.5rem 0 0;padding:0;display:grid;grid-gap:.55rem;gap:.55rem}.ai-side-list li{padding:.7rem .8rem;border-radius:.7rem;background:rgba(10,28,46,.03);border:1px solid transparent;color:var(--ink-soft);font-size:.9rem;line-height:1.5}.ai-side-list li strong{display:block;color:var(--ink);margin-bottom:.15rem;font-size:.92rem}.ai-error{margin:.35rem 0 0;color:var(--danger);font-size:.9rem}@media (max-width:900px){.ai-layout{grid-template-columns:1fr}}.ncbi-mode-card,.rnaseq-panel,.tool-post-card{background:var(--paper-elevated)}.ncbi-checklist-head h3,.ncbi-mode-card h3,.rnaseq-ann-box h3,.tool-post-card h3{font-family:var(--font-display);font-size:var(--h3-size);font-weight:650;line-height:var(--h3-lh);color:var(--ink)}.site-header{-webkit-backdrop-filter:blur(10px);backdrop-filter:blur(10px)}.nav-link{border-radius:999px;padding:.35rem .7rem;transition:background .14s ease,color .14s ease}.nav-link:hover{background:var(--accent-soft);color:var(--accent-ink)}